Publications
2024
 
      
    
    
      
      
      
        Guided wave elastography of human skins with a layered model incorporating the effect of muscle state
      
      
      
  
        Journal of Biomechanics
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        01 Sep 2024
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        doi:10.1016/j.jbiomech.2024.112279
      
      
        
        
        
      
     
      
    
    
      
      
      
        In Vivo Optical Coherence Elastography Unveils Spatial Variation of Human Corneal Stiffness
      
      
      
  
        IEEE Transactions on Biomedical Engineering
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        01 May 2024
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        doi:10.1109/TBME.2023.3338086
      
      
        
          
            In this work, we demonstrate the biomechanical heterogeneity of the cornea via high-resolution OCE, enabling early detection and staging of corneal diseases
          
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        SWENet: A Physics-Informed Deep Neural Network (PINN) for Shear Wave Elastography
      
      
      
  
        IEEE Transactions on Medical Imaging
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        01 Apr 2024
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        doi:10.1109/TMI.2023.3338178
      
      
        
          
            This work establishes full-waveform inversion for near-field shear waves using deep learning, enabling super-resolution shear wave imaging
          
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        Simultaneous tensile and shear measurement of the human cornea in vivo using S0- and A0-wave optical coherence elastography
      
      
      
  
        Acta Biomaterialia
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        01 Feb 2024
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        doi:10.1016/j.actbio.2023.12.019
      
      
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        High-Frequency Optical Coherence Elastography for Gingival Tissue Characterization: Variability in Stiffness and Response to Physiological Conditions
      
      
      
  
        Biomaterials Research
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        01 Jan 2024
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        doi:10.34133/bmr.0044
      
      
        
        
        
      
    2023
 
      
    
    
      
      
      
        Ultra-wideband optical coherence elastography from acoustic to ultrasonic frequencies
      
      
      
  
        Nature Communications
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        16 Aug 2023
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        doi:10.1038/s41467-023-40625-y
      
      
        
          
            This article demonstrates the first ultrasonic shear wave imaging technique
          
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        Noninvasive measurement of local stress inside soft materials with programmed shear waves
      
      
      
  
        Science Advances
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        10 Mar 2023
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        doi:10.1126/sciadv.add4082
      
      
        
          
            This article proposes an acoustoelastic theory that lays the foundation for stress measurement without requiring knowledge of constitutive parameters
          
        
        
        
          
  
        
      
    2022
 
      
    
    
      
      
      
        Supershear surface waves reveal prestress and anisotropy of soft materials
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 Dec 2022
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        doi:10.1016/j.jmps.2022.105085
      
      
        
          
            In this work, we demonstrate that the supershear surface wave is consistently supported in solids, irrespective of the shear quality factor
          
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        Non-destructive mapping of stress and strain in soft thin films through sound waves
      
      
      
  
        Communications Physics
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        17 Sep 2022
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        doi:10.1038/s42005-022-01000-3
      
      
        
        
        
      
     
      
    
    
      
      
      
        In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography
      
      
      
  
        Acta Biomaterialia
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        01 Jul 2022
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        doi:10.1016/j.actbio.2022.04.030
      
      
        
        
        
      
     
      
    
    
      
      
      
        Arterial Stiffness Probed by Dynamic Ultrasound Elastography Characterizes Waveform of Blood Pressure
      
      
      
  
        IEEE Transactions on Medical Imaging
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        01 Jun 2022
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        doi:10.1109/TMI.2022.3141613
      
      
        
          
            In this work, we demonstrate the dynamic changes of arterial stiffness within cardiac cycles and find a scaling law between shear wave speed and local blood pressure
          
        
        
        
          
  
        
      
    2021
 
      
    
    
      
      
      
        AFM-based indentation method for measuring the relaxation property of living cells
      
      
      
  
        Journal of Biomechanics
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        01 Jun 2021
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        doi:10.1016/j.jbiomech.2021.110444
      
      
        
        
        
      
    2020
 
      
    
    
      
      
      
        An ultrasonic method to measure stress without calibration: The angled shear wave method
      
      
      
  
        The Journal of the Acoustical Society of America
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        01 Dec 2020
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        doi:10.1121/10.0002959
      
      
        
        
        
      
     
      
    
    
      
      
      
        Backward Mach cone of shear waves induced by a moving force in soft anisotropic materials
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 May 2020
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        doi:10.1016/j.jmps.2020.103896
      
      
        
          
            This work demonstrates the mechanism of backward shear wave Mach cone in anisotropic solids
          
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        Size effect in shear wave elastography of small solid tumors – A phantom study
      
      
      
  
        Extreme Mechanics Letters
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        01 Feb 2020
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        doi:10.1016/j.eml.2020.100636
      
      
        
        
        
      
    2019
 
      
    
    
      
      
      
        Mechanical characterization of functionally graded soft materials with ultrasound elastography
      
      
      
  
        Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
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        18 Mar 2019
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        doi:10.1098/rsta.2018.0075
      
      
        
        
        
      
     
      
    
    
      
      
      
        Indentation creep tests to assess the viscoelastic properties of soft materials: Theory, method and experiment
      
      
      
  
        International Journal of Non-Linear Mechanics
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        01 Mar 2019
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        doi:10.1016/j.ijnonlinmec.2018.12.005
      
      
        
        
        
      
     
      
    
    
      
      
      
        Elastodiagnosis of diseases: A review
      
      
      
  
        Extreme Mechanics Letters
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        01 Feb 2019
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        doi:10.1016/j.eml.2019.01.009
      
      
        
        
        
      
     
      
    
    
      
      
      
        Guided wave elastography of layered soft tissues
      
      
      
  
        Acta Biomaterialia
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        01 Jan 2019
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        doi:10.1016/j.actbio.2018.12.002
      
      
        
        
        
      
    2018
 
      
    
    
      
      
      
        In vivo and ex vivo elastic properties of brain tissues measured with ultrasound elastography
      
      
      
  
        Journal of the Mechanical Behavior of Biomedical Materials
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        01 Jul 2018
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        doi:10.1016/j.jmbbm.2018.04.017
      
      
        
        
        
      
     
      
    
    
      
      
      
        Effect of ligation on the viscoelastic properties of liver tissues
      
      
      
  
        Journal of Biomechanics
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        01 Jul 2018
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        doi:10.1016/j.jbiomech.2018.05.018
      
      
        
        
        
      
     
      
    
    
      
      
      
        Non-leaky modes and bandgaps of surface acoustic waves in wrinkled stiff-film/compliant-substrate bilayers
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 Mar 2018
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        doi:10.1016/j.jmps.2017.11.024
      
      
        
          
            This work demonstrates the effects of surface wrinkling on surface wave propagation for the first time
          
        
        
        
          
  
        
      
    2017
      
      
      
        Tissue-mimicking materials for elastography phantoms: A review
      
      
      
  
        Extreme Mechanics Letters
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        01 Nov 2017
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        doi:10.1016/j.eml.2017.09.009
      
      
        
        
        
      
    
      
      
      
        Notice of Removal: Guided wave elastography of pressurized artery in both longitudinal and transverse sections: Validation in phantom experiments
      
      
      
  
        2017 IEEE International Ultrasonics Symposium (IUS)
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        01 Sep 2017
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        doi:10.1109/ULTSYM.2017.8091785
      
      
        
        
        
      
    
      
      
      
        Notice of Removal: Guided wave elastography of press-stressed thin-walled soft tissues
      
      
      
  
        2017 IEEE International Ultrasonics Symposium (IUS)
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        01 Sep 2017
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        doi:10.1109/ULTSYM.2017.8091957
      
      
        
        
        
      
    
      
      
      
        Comparison of different motion estimation methods for vessel cross-sectional shear wave imaging
      
      
      
  
        2017 IEEE International Ultrasonics Symposium (IUS)
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        01 Sep 2017
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        doi:10.1109/ULTSYM.2017.8092805
      
      
        
        
        
      
    
      
      
      
        Comparison of different motion estimation methods for vessel cross-sectional shear wave imaging
      
      
      
  
        2017 IEEE International Ultrasonics Symposium (IUS)
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        01 Sep 2017
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        doi:10.1109/ULTSYM.2017.8092267
      
      
        
        
        
      
    
      
      
      
        Assessing the mechanical properties of anisotropic soft tissues using guided wave elastography: Inverse method and numerical experiments
      
      
      
  
        The Journal of the Acoustical Society of America
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        01 Sep 2017
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        doi:10.1121/1.5002685
      
      
        
        
        
      
    
      
      
      
        Novel Method for Vessel Cross-Sectional Shear Wave Imaging
      
      
      
  
        Ultrasound in Medicine & Biology
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        01 Jul 2017
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        doi:10.1016/j.ultrasmedbio.2017.03.001
      
      
        
        
        
      
    
      
      
      
        Edge wrinkling of a soft ridge with gradient thickness
      
      
      
  
        Applied Physics Letters
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        05 Jun 2017
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        doi:10.1063/1.4985009
      
      
        
        
        
      
     
      
    
    
      
      
      
        Guided waves in pre-stressed hyperelastic plates and tubes: Application to the ultrasound elastography of thin-walled soft materials
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 May 2017
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        doi:10.1016/j.jmps.2017.02.008
      
      
        
          
            This work establishes the first acoustoelastic model for shear wave imaging of thin-walled tissues
          
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        Mechanics of ultrasound elastography
      
      
      
  
        Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
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        01 Mar 2017
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        doi:10.1098/rspa.2016.0841
      
      
        
          
            This is a comprehensive review on the mechanics of ultrasound elastography
          
        
        
        
          
  
        
      
    
      
      
      
        Wrinkling of a stiff film resting on a fiber-filled soft substrate and its potential application as tunable metamaterials
      
      
      
  
        Extreme Mechanics Letters
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        01 Feb 2017
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        doi:10.1016/j.eml.2016.12.002
      
      
        
        
        
      
    
      
      
      
        An Inverse Method to Determine Arterial Stiffness with Guided Axial Waves
      
      
      
  
        Ultrasound in Medicine & Biology
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        01 Feb 2017
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        doi:10.1016/j.ultrasmedbio.2016.10.006
      
      
        
        
        
      
    
      
      
      
        Temperature-dependent elastic properties of brain tissues measured with the shear wave elastography method
      
      
      
  
        Journal of the Mechanical Behavior of Biomedical Materials
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        01 Jan 2017
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        doi:10.1016/j.jmbbm.2016.09.026
      
      
        
        
        
      
    
      
      
      
        An ultrasound elastography method to determine the local stiffness of arteries with guided circumferential waves
      
      
      
  
        Journal of Biomechanics
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        01 Jan 2017
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        doi:10.1016/j.jbiomech.2016.12.006
      
      
        
        
        
      
    2016
      
      
      
        Tunable defect mode in a soft wrinkled bilayer system
      
      
      
  
        Extreme Mechanics Letters
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        01 Dec 2016
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        doi:10.1016/j.eml.2016.06.005
      
      
        
        
        
      
     
      
    
    
      
      
      
        Elastic Cherenkov effects in transversely isotropic soft materials-I: Theoretical analysis, simulations and inverse method
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 Nov 2016
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        doi:10.1016/j.jmps.2016.05.023
      
      
        
        
        
          
  
        
      
     
      
    
    
      
      
      
        Elastic Cherenkov effects in transversely isotropic soft materials-II: Ex vivo and in vivo experiments
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 Sep 2016
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        doi:10.1016/j.jmps.2016.04.028
      
      
        
        
        
          
  
        
      
    
      
      
      
        Controlling elastic wave propagation in a soft bilayer system via wrinkling-induced stress patterns
      
      
      
  
        Soft Matter
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        01 Jan 2016
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        doi:10.1039/c6sm00265j
      
      
        
        
        
      
    2015
      
      
      
        Effect of lateral dimension on the surface wrinkling of a thin film on compliant substrate induced by differential growth/swelling
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 Oct 2015
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        doi:10.1016/j.jmps.2015.06.003
      
      
        
        
        
      
    
      
      
      
        Determining the in vivo elastic properties of dermis layer of human skin using the supersonic shear imaging technique and inverse analysis
      
      
      
  
        Medical Physics
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        12 Jun 2015
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        doi:10.1118/1.4922133
      
      
        
        
        
      
    
      
      
      
        Measuring the linear and nonlinear elastic properties of brain tissue with shear waves and inverse analysis
      
      
      
  
        Biomechanics and Modeling in Mechanobiology
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        20 Feb 2015
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        doi:10.1007/s10237-015-0658-0
      
      
        
        
        
      
     
      
    
    
      
      
      
        Characterization of the nonlinear elastic properties of soft tissues using the supersonic shear imaging (SSI) technique: Inverse method, ex vivo and in vivo experiments
      
      
      
  
        Medical Image Analysis
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        01 Feb 2015
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        doi:10.1016/j.media.2014.10.010
      
      
        
        
        
          
  
        
      
    2014
      
      
      
        Pipette aspiration of hyperelastic compliant materials: Theoretical analysis, simulations and experiments
      
      
      
  
        Journal of the Mechanics and Physics of Solids
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        01 Aug 2014
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        doi:10.1016/j.jmps.2014.03.012
      
      
        
        
        
      
    
      
      
      
        Determination of the Reduced Creep Function of Viscoelastic Compliant Materials Using Pipette Aspiration Method
      
      
      
  
        Journal of Applied Mechanics
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        01 Apr 2014
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        doi:10.1115/1.4027159
      
      
        
        
        
      
    2013
      
      
      
        Spherical indentation method for determining the constitutive parameters of hyperelastic soft materials
      
      
      
  
        Biomechanics and Modeling in Mechanobiology
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        13 Mar 2013
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        doi:10.1007/s10237-013-0481-4