Publications

2024

Guided wave elastography of human skins with a layered model incorporating the effect of muscle state
Guided wave elastography of human skins with a layered model incorporating the effect of muscle state
Shiyu Ma, Zhaoyi Zhang, Guo-Yang Li, Yanping Cao
Journal of Biomechanics  ·  01 Sep 2024  ·  doi:10.1016/j.jbiomech.2024.112279
In Vivo Optical Coherence Elastography Unveils Spatial Variation of Human Corneal Stiffness
In Vivo Optical Coherence Elastography Unveils Spatial Variation of Human Corneal Stiffness
Guo-Yang Li, Xu Feng, Seok-Hyun Yun
IEEE Transactions on Biomedical Engineering  ·  01 May 2024  ·  doi:10.1109/TBME.2023.3338086
In this work, we demonstrate the biomechanical heterogeneity of the cornea via high-resolution OCE, enabling early detection and staging of corneal diseases
SWENet: A Physics-Informed Deep Neural Network (PINN) for Shear Wave Elastography
SWENet: A Physics-Informed Deep Neural Network (PINN) for Shear Wave Elastography
Ziying Yin, Guo-Yang Li, Zhaoyi Zhang, Yang Zheng, Yanping Cao
IEEE Transactions on Medical Imaging  ·  01 Apr 2024  ·  doi:10.1109/TMI.2023.3338178
This work establishes full-waveform inversion for near-field shear waves using deep learning, enabling super-resolution shear wave imaging
High-Frequency Optical Coherence Elastography for Gingival Tissue Characterization: Variability in Stiffness and Response to Physiological Conditions
High-Frequency Optical Coherence Elastography for Gingival Tissue Characterization: Variability in Stiffness and Response to Physiological Conditions
Wonjoon Moon, Xu Feng, Guo-Yang Li, Seok-Hyun Yun
Biomaterials Research  ·  01 Jan 2024  ·  doi:10.34133/bmr.0044

2023

Ultra-wideband optical coherence elastography from acoustic to ultrasonic frequencies
Ultra-wideband optical coherence elastography from acoustic to ultrasonic frequencies
Xu Feng, Guo-Yang Li, Seok-Hyun Yun
Nature Communications  ·  16 Aug 2023  ·  doi:10.1038/s41467-023-40625-y
This article demonstrates the first ultrasonic shear wave imaging technique
Noninvasive measurement of local stress inside soft materials with programmed shear waves
Noninvasive measurement of local stress inside soft materials with programmed shear waves
Zhaoyi Zhang, Guo-Yang Li, Yuxuan Jiang, Yang Zheng, Artur L. Gower, Michel Destrade, Yanping Cao
Science Advances  ·  10 Mar 2023  ·  doi:10.1126/sciadv.add4082
This article proposes an acoustoelastic theory that lays the foundation for stress measurement without requiring knowledge of constitutive parameters

2022

Supershear surface waves reveal prestress and anisotropy of soft materials
Supershear surface waves reveal prestress and anisotropy of soft materials
Guo-Yang Li, Xu Feng, Antoine Ramier, Seok-Hyun Yun
Journal of the Mechanics and Physics of Solids  ·  01 Dec 2022  ·  doi:10.1016/j.jmps.2022.105085
In this work, we demonstrate that the supershear surface wave is consistently supported in solids, irrespective of the shear quality factor
Non-destructive mapping of stress and strain in soft thin films through sound waves
Non-destructive mapping of stress and strain in soft thin films through sound waves
Guo-Yang Li, Artur L. Gower, Michel Destrade, Seok-Hyun Yun
Communications Physics  ·  17 Sep 2022  ·  doi:10.1038/s42005-022-01000-3
In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography
In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography
Xu Feng, Guo-Yang Li, Antoine Ramier, Amira M. Eltony, Seok-Hyun Yun
Acta Biomaterialia  ·  01 Jul 2022  ·  doi:10.1016/j.actbio.2022.04.030
Arterial Stiffness Probed by Dynamic Ultrasound Elastography Characterizes Waveform of Blood Pressure
Arterial Stiffness Probed by Dynamic Ultrasound Elastography Characterizes Waveform of Blood Pressure
Guo-Yang Li, Yuxuan Jiang, Yang Zheng, Weiqiang Xu, Zhaoyi Zhang, Yanping Cao
IEEE Transactions on Medical Imaging  ·  01 Jun 2022  ·  doi:10.1109/TMI.2022.3141613
In this work, we demonstrate the dynamic changes of arterial stiffness within cardiac cycles and find a scaling law between shear wave speed and local blood pressure

2021

AFM-based indentation method for measuring the relaxation property of living cells
AFM-based indentation method for measuring the relaxation property of living cells
Jun-Yuan Sheng, Chi Mo, Guo-Yang Li, Hu-Cheng Zhao, Yanping Cao, Xi-Qiao Feng
Journal of Biomechanics  ·  01 Jun 2021  ·  doi:10.1016/j.jbiomech.2021.110444

2020

An ultrasonic method to measure stress without calibration: The angled shear wave method
An ultrasonic method to measure stress without calibration: The angled shear wave method
Guo-Yang Li, Artur L. Gower, Michel Destrade
The Journal of the Acoustical Society of America  ·  01 Dec 2020  ·  doi:10.1121/10.0002959
Backward Mach cone of shear waves induced by a moving force in soft anisotropic materials
Backward Mach cone of shear waves induced by a moving force in soft anisotropic materials
Guo-Yang Li, Yanping Cao
Journal of the Mechanics and Physics of Solids  ·  01 May 2020  ·  doi:10.1016/j.jmps.2020.103896
This work demonstrates the mechanism of backward shear wave Mach cone in anisotropic solids
Size effect in shear wave elastography of small solid tumors – A phantom study
Size effect in shear wave elastography of small solid tumors – A phantom study
Yanfeng Zhang, Guo-Yang Li, Jianqiao Zhou, Yang Zheng, Yu-Xuan Jiang, Yan-Lin Liu, Li-Li Zhang, Lin-Xue Qian, Yanping Cao
Extreme Mechanics Letters  ·  01 Feb 2020  ·  doi:10.1016/j.eml.2020.100636

2019

Mechanical characterization of functionally graded soft materials with ultrasound elastography
Mechanical characterization of functionally graded soft materials with ultrasound elastography
Guo-Yang Li, Zhao-Yi Zhang, Jialin Qian, Yang Zheng, Wenli Liu, Huijuan Wu, Yanping Cao
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences  ·  18 Mar 2019  ·  doi:10.1098/rsta.2018.0075
Indentation creep tests to assess the viscoelastic properties of soft materials: Theory, method and experiment
Indentation creep tests to assess the viscoelastic properties of soft materials: Theory, method and experiment
Xiao Zhang, Yang Zheng, Guo-Yang Li, Yan-Lin Liu, Yanping Cao
International Journal of Non-Linear Mechanics  ·  01 Mar 2019  ·  doi:10.1016/j.ijnonlinmec.2018.12.005
Elastodiagnosis of diseases: A review
Elastodiagnosis of diseases: A review
Yanping Cao, Yang Zheng, Guo-Yang Li, Yuxuan Jiang
Extreme Mechanics Letters  ·  01 Feb 2019  ·  doi:10.1016/j.eml.2019.01.009
Guided wave elastography of layered soft tissues
Guided wave elastography of layered soft tissues
Guo-Yang Li, Yang Zheng, Yu-Xuan Jiang, Zhaoyi Zhang, Yanping Cao
Acta Biomaterialia  ·  01 Jan 2019  ·  doi:10.1016/j.actbio.2018.12.002

2018

In vivo and ex vivo elastic properties of brain tissues measured with ultrasound elastography
In vivo and ex vivo elastic properties of brain tissues measured with ultrasound elastography
Yan-Lin Liu, Dong Liu, Liang Xu, Chen Su, Guo-Yang Li, Lin-Xue Qian, Yanping Cao
Journal of the Mechanical Behavior of Biomedical Materials  ·  01 Jul 2018  ·  doi:10.1016/j.jmbbm.2018.04.017
Effect of ligation on the viscoelastic properties of liver tissues
Effect of ligation on the viscoelastic properties of liver tissues
Dong Liu, Guo-Yang Li, Chen Su, Yang Zheng, Yu-Xuan Jiang, Lin-Xue Qian, Yanping Cao
Journal of Biomechanics  ·  01 Jul 2018  ·  doi:10.1016/j.jbiomech.2018.05.018
Non-leaky modes and bandgaps of surface acoustic waves in wrinkled stiff-film/compliant-substrate bilayers
Non-leaky modes and bandgaps of surface acoustic waves in wrinkled stiff-film/compliant-substrate bilayers
Guo-Yang Li, Guoqiang Xu, Yang Zheng, Yanping Cao
Journal of the Mechanics and Physics of Solids  ·  01 Mar 2018  ·  doi:10.1016/j.jmps.2017.11.024
This work demonstrates the effects of surface wrinkling on surface wave propagation for the first time

2017

Tissue-mimicking materials for elastography phantoms: A review
Tissue-mimicking materials for elastography phantoms: A review
Yanping Cao, Guo-Yang Li, Xiao Zhang, Yan-Lin Liu
Extreme Mechanics Letters  ·  01 Nov 2017  ·  doi:10.1016/j.eml.2017.09.009
Notice of Removal: Guided wave elastography of pressurized artery in both longitudinal and transverse sections: Validation in phantom experiments
Notice of Removal: Guided wave elastography of pressurized artery in both longitudinal and transverse sections: Validation in phantom experiments
Qiong He, Guoyang Li, Yanping Cao, Jianwen Luo
2017 IEEE International Ultrasonics Symposium (IUS)  ·  01 Sep 2017  ·  doi:10.1109/ULTSYM.2017.8091785
Notice of Removal: Guided wave elastography of press-stressed thin-walled soft tissues
Notice of Removal: Guided wave elastography of press-stressed thin-walled soft tissues
Guo-Yang Li, Qiong He, Robert Mangan, Guo-Qiang Xu, Jianwen Luo, Michel Destrade, Yanping Cao
2017 IEEE International Ultrasonics Symposium (IUS)  ·  01 Sep 2017  ·  doi:10.1109/ULTSYM.2017.8091957
Comparison of different motion estimation methods for vessel cross-sectional shear wave imaging
Comparison of different motion estimation methods for vessel cross-sectional shear wave imaging
Qiong He, Guo-Yang Li, Yanping Cao, Jianwen Luo
2017 IEEE International Ultrasonics Symposium (IUS)  ·  01 Sep 2017  ·  doi:10.1109/ULTSYM.2017.8092805
Comparison of different motion estimation methods for vessel cross-sectional shear wave imaging
Comparison of different motion estimation methods for vessel cross-sectional shear wave imaging
Qiong He, Guoyang Li, Yanping Cao, Jianwen Luo
2017 IEEE International Ultrasonics Symposium (IUS)  ·  01 Sep 2017  ·  doi:10.1109/ULTSYM.2017.8092267
Assessing the mechanical properties of anisotropic soft tissues using guided wave elastography: Inverse method and numerical experiments
Assessing the mechanical properties of anisotropic soft tissues using guided wave elastography: Inverse method and numerical experiments
Guo-Yang Li, Yanping Cao
The Journal of the Acoustical Society of America  ·  01 Sep 2017  ·  doi:10.1121/1.5002685
Novel Method for Vessel Cross-Sectional Shear Wave Imaging
Novel Method for Vessel Cross-Sectional Shear Wave Imaging
Qiong He, Guo-Yang Li, Fu-Feng Lee, Qihao Zhang, Yanping Cao, Jianwen Luo
Ultrasound in Medicine & Biology  ·  01 Jul 2017  ·  doi:10.1016/j.ultrasmedbio.2017.03.001
Edge wrinkling of a soft ridge with gradient thickness
Edge wrinkling of a soft ridge with gradient thickness
Yan Zhao, Zhi-Chun Shao, Guo-Yang Li, Yang Zheng, Wan-Yu Zhang, Bo Li, Yanping Cao, Xi-Qiao Feng
Applied Physics Letters  ·  05 Jun 2017  ·  doi:10.1063/1.4985009
Guided waves in pre-stressed hyperelastic plates and tubes: Application to the ultrasound elastography of thin-walled soft materials
Guided waves in pre-stressed hyperelastic plates and tubes: Application to the ultrasound elastography of thin-walled soft materials
Guo-Yang Li, Qiong He, Robert Mangan, Guoqiang Xu, Chi Mo, Jianwen Luo, Michel Destrade, Yanping Cao
Journal of the Mechanics and Physics of Solids  ·  01 May 2017  ·  doi:10.1016/j.jmps.2017.02.008
This work establishes the first acoustoelastic model for shear wave imaging of thin-walled tissues
Mechanics of ultrasound elastography
Mechanics of ultrasound elastography
Guo-Yang Li, Yanping Cao
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences  ·  01 Mar 2017  ·  doi:10.1098/rspa.2016.0841
This is a comprehensive review on the mechanics of ultrasound elastography
Wrinkling of a stiff film resting on a fiber-filled soft substrate and its potential application as tunable metamaterials
Wrinkling of a stiff film resting on a fiber-filled soft substrate and its potential application as tunable metamaterials
Yang Zheng, Guo-Yang Li, Yanping Cao, Xi-Qiao Feng
Extreme Mechanics Letters  ·  01 Feb 2017  ·  doi:10.1016/j.eml.2016.12.002
An Inverse Method to Determine Arterial Stiffness with Guided Axial Waves
An Inverse Method to Determine Arterial Stiffness with Guided Axial Waves
Guo-Yang Li, Qiong He, Lin Jia, Ping He, Jianwen Luo, Yanping Cao
Ultrasound in Medicine & Biology  ·  01 Feb 2017  ·  doi:10.1016/j.ultrasmedbio.2016.10.006
Temperature-dependent elastic properties of brain tissues measured with the shear wave elastography method
Temperature-dependent elastic properties of brain tissues measured with the shear wave elastography method
Yan-Lin Liu, Guo-Yang Li, Ping He, Ze-Qi Mao, Yanping Cao
Journal of the Mechanical Behavior of Biomedical Materials  ·  01 Jan 2017  ·  doi:10.1016/j.jmbbm.2016.09.026
An ultrasound elastography method to determine the local stiffness of arteries with guided circumferential waves
An ultrasound elastography method to determine the local stiffness of arteries with guided circumferential waves
Guo-Yang Li, Qiong He, Guoqiang Xu, Lin Jia, Jianwen Luo, Yanping Cao
Journal of Biomechanics  ·  01 Jan 2017  ·  doi:10.1016/j.jbiomech.2016.12.006

2016

Tunable defect mode in a soft wrinkled bilayer system
Tunable defect mode in a soft wrinkled bilayer system
Guo-Yang Li, Yang Zheng, Yanping Cao
Extreme Mechanics Letters  ·  01 Dec 2016  ·  doi:10.1016/j.eml.2016.06.005
Elastic Cherenkov effects in transversely isotropic soft materials-I: Theoretical analysis, simulations and inverse method
Elastic Cherenkov effects in transversely isotropic soft materials-I: Theoretical analysis, simulations and inverse method
Guo-Yang Li, Yang Zheng, Yanlin Liu, Michel Destrade, Yanping Cao
Journal of the Mechanics and Physics of Solids  ·  01 Nov 2016  ·  doi:10.1016/j.jmps.2016.05.023
Elastic Cherenkov effects in transversely isotropic soft materials-II: Ex vivo and in vivo experiments
Elastic Cherenkov effects in transversely isotropic soft materials-II: Ex vivo and in vivo experiments
Guo-Yang Li, Qiong He, Lin-Xue Qian, Huiying Geng, Yanlin Liu, Xue-Yi Yang, Jianwen Luo, Yanping Cao
Journal of the Mechanics and Physics of Solids  ·  01 Sep 2016  ·  doi:10.1016/j.jmps.2016.04.028
Controlling elastic wave propagation in a soft bilayer system via wrinkling-induced stress patterns
Controlling elastic wave propagation in a soft bilayer system via wrinkling-induced stress patterns
Guo-Yang Li, Yang Zheng, Yanping Cao, Xi-Qiao Feng, Wanyu Zhang
Soft Matter  ·  01 Jan 2016  ·  doi:10.1039/c6sm00265j

2015

Effect of lateral dimension on the surface wrinkling of a thin film on compliant substrate induced by differential growth/swelling
Effect of lateral dimension on the surface wrinkling of a thin film on compliant substrate induced by differential growth/swelling
Yan Zhao, Xue Han, Guoyang Li, Conghua Lu, Yanping Cao, Xi-Qiao Feng, Huajian Gao
Journal of the Mechanics and Physics of Solids  ·  01 Oct 2015  ·  doi:10.1016/j.jmps.2015.06.003
Determining the <i>in vivo</i> elastic properties of dermis layer of human skin using the supersonic shear imaging technique and inverse analysis
Determining the in vivo elastic properties of dermis layer of human skin using the supersonic shear imaging technique and inverse analysis
Cheng‐Cheng Luo, Lin‐Xue Qian, Guo‐Yang Li, Yi Jiang, Si Liang, Yanping Cao
Medical Physics  ·  12 Jun 2015  ·  doi:10.1118/1.4922133
Measuring the linear and nonlinear elastic properties of brain tissue with shear waves and inverse analysis
Measuring the linear and nonlinear elastic properties of brain tissue with shear waves and inverse analysis
Yi Jiang, Guoyang Li, Lin-Xue Qian, Si Liang, Michel Destrade, Yanping Cao
Biomechanics and Modeling in Mechanobiology  ·  20 Feb 2015  ·  doi:10.1007/s10237-015-0658-0

2014

Pipette aspiration of hyperelastic compliant materials: Theoretical analysis, simulations and experiments
Pipette aspiration of hyperelastic compliant materials: Theoretical analysis, simulations and experiments
Man-Gong Zhang, Yan-Ping Cao, Guo-Yang Li, Xi-Qiao Feng
Journal of the Mechanics and Physics of Solids  ·  01 Aug 2014  ·  doi:10.1016/j.jmps.2014.03.012
Determination of the Reduced Creep Function of Viscoelastic Compliant Materials Using Pipette Aspiration Method
Determination of the Reduced Creep Function of Viscoelastic Compliant Materials Using Pipette Aspiration Method
Yan-Ping Cao, Guo-Yang Li, Man-Gong Zhang, Xi-Qiao Feng
Journal of Applied Mechanics  ·  01 Apr 2014  ·  doi:10.1115/1.4027159

2013

Spherical indentation method for determining the constitutive parameters of hyperelastic soft materials
Spherical indentation method for determining the constitutive parameters of hyperelastic soft materials
Man-Gong Zhang, Yan-Ping Cao, Guo-Yang Li, Xi-Qiao Feng
Biomechanics and Modeling in Mechanobiology  ·  13 Mar 2013  ·  doi:10.1007/s10237-013-0481-4